吡拉西坦治疗创伤性脑水肿62例疗效观察
丁绪元刘大军钱中琪(江苏省泰州市第二人民医院神经外科 225500)
【摘要】目的:观察吡拉西坦注射液治疗创伤性脑水肿的临床效果。方法:将我院近一年收治的62例创伤性脑水肿患者62例随机分为对照组和治疗组,其中:治疗组31例,静滴20%吡拉西坦注射液治疗;对照组31例,静滴20%甘露醇治疗。通过患者的头痛、呕吐症状,意识状态的变化,视乳头水肿以及头颅CT水肿带的好转等,观察药物的疗效。通过测定两组治疗前后肾功能以及血电解质的变化,观察药物的副作用。结果:治疗组显效4例,有效24例,无效2例;对照组显效5例,有效22例,%%,无显著性差异(P>)。在用药期间和用药后治疗组没有观察到与所用药品有关的副作用,对照组有一例用药5天后出现甘露醇肾病。结论:吡拉西坦注射液治疗创伤性脑水肿疗效肯定且安全,值得临床推广。
【关键词】吡拉西坦注射液颅脑损伤脑水肿
【中图分类号】R453 【文献标识码】A 【文章编号】2095-1752(2013)26-0155-02
Observation on Curative Effect of Piracetam Injection in Patients with traumatic brain edema 62 cases
DING Xu-yuan LIU Da-jun QIANA Zhong-qi
(Department of Neurosurgery,The Second People's Hospital of Taizhou,Taizhou 225500,china)
【Abstract】Objective :To investigate the effect of piracetam injection on reduction the traumatic brain edema. Methods:62 patients with traumatic encephaledemal were divided into the treatment group and the control group,31 cases were injected by the 20% piracetam injection,the other 31 cases were injected by the 20% mannitol..Observing the manifestation including
headach,vomit,consciousness,papilledma and encephaledema of cranial CT,Determining the change of renal function and electrolyte in : The total effective rate of two group was % and %,no significant diffevence(P>).No adverse reactions was observed in the treatment group during a
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