企业财务战略研究.doc

企业财务战略研究.docReview of Antibiotics
Zagorka Popovski, .
Clinical Pharmacist, Intensive Care
Cephalosporins
Gram +
1st Generation
•Ancef
•Keflex
LESS IS MORE!!!
Timing of pre op antibiotic is key
POPOVSKI and TEOHSCCM 1993 SAN DIEGO CA
REDUCTION OF POST-OP ANTIBIOTICS FROM 72 HR TO 48HR
ADMINISTER PRE-OP ANTIBIOTIC IN OR
WOUND INFECTION RATE REDUCED FROM 2% TO %
Cephalosporins
Gram + Gram + Coverage plus:
1st Generation •Ecoli
•Ancef •Proteus
•Keflex •Klebsiella
Cephalosporins
Gram +
1st Generation 2nd Generation
•Ancef •Cefuroxime
•Keflex •Cefamandole
•Cefotetan +/- anaerobe
•Cefoxitin
H Flu
Cephalosporins
Gram + Gram -
1st Generation 2nd Generation 3rd Generation
•Ancef •Cefuroxime •Ceftriaxone
•Keflex •Cefamandole •Cefotaxime
•Cefotetan •Ceftazidime
•Cefoxitin
Cephalosporins
Gram - Gram - Coverage
*3rd Generation obacter
Serratia
•Ceftriaxone (CNS ration, gram neg. alternative to amnioglycosides)
•Cefotaxime

•Ceftazidime •Pseudomonas Aeruginosa
*not for enterobacter
Penicillins
Penicillin Ampicillin Cloxacillin
Amoxillin Oxacillin
Nafcillin
Methicillin
®
Penicillins
Coverage
•Ampicillin •us
•Amoxicillin •Ecoli
•Klebsiella
•Proteus
•H. Flu
Clavulin®=amoxicillin+clavulinic acid