该【利用PET-MRI勾画头颈部鳞癌GTV靶区并连续评估肿瘤放射治疗反应的研究 】是由【niuwk】上传分享，文档一共【2】页，该文档可以免费在线阅读，需要了解更多关于【利用PET-MRI勾画头颈部鳞癌GTV靶区并连续评估肿瘤放射治疗反应的研究 】的内容，可以使用淘豆网的站内搜索功能，选择自己适合的文档，以下文字是截取该文章内的部分文字，如需要获得完整电子版，请下载此文档到您的设备，方便您编辑和打印。利用PET-MRI勾画头颈部鳞癌GTV靶区并连续评估肿瘤放射治疗反应的研究 英文题目：Using PET-MRI to delineate GTV of head and neck squamous cell carcinoma and assess tumor response to radiotherapy 摘要：头颈部鳞癌是一种较常见的恶性肿瘤，放射治疗是其一个主要的治疗手段。本文利用PET-MRI技术勾画头颈部鳞癌的GTV靶区，并通过连续的评估肿瘤放射治疗反应的研究，探讨PET-MRI技术在肿瘤治疗中的应用价值。我们对20名头颈部鳞癌患者进行PET-MRI扫描，并使用软件对图像进行分析和勾画。经过放射治疗后，我们对每个患者的GTV进行定量评估，并对治疗效果进行监控。结果显示：PET-MRI技术勾画的GTV较传统的CT-MRI技术勾画的GTV更加精准，放疗反应评估也更加可靠。同时，PET-MRI还可以提供血管生成和代谢活动等信息用于研究。因此，我们认为PET-MRI技术在头颈部鳞癌的诊断和治疗中具有显著优势，在未来肿瘤治疗中具有广泛的应用前景。 关键词：头颈部鳞癌；PET-MRI；GTV；放疗反应；治疗监控。 Introduction: Head and neck squamous cell carcinoma (HNSCC) is a common malignant tumor, and radiotherapy is one of the main treatment options. Accurate delineation of the gross tumor volume (GTV) is critical for the success of radiotherapy in HNSCC. PET-MRI is a new imaging technology that integrates the advantages of positron emission tomography (PET) and magnetic resonance imaging (MRI). In this study, we aim to explore the value of PET-MRI in the delineation of GTV and continuous evaluation of tumor response to radiotherapy in HNSCC. Materials and methods: Twenty patients with HNSCC were recruited in this study. All patients underwent PET-MRI scans before and after radiotherapy. PET-MRI images were analyzed and GTV was delineated using software. The response of the tumor to radiotherapy was monitored continuously by assessing GTV of each patient quantitatively. Results: PET-MRI delineation of GTV was found to be more accurate compared to traditional CT-MRI technique. The evaluation of therapeutic response after radiotherapy was more reliable using PET-MRI technology. Besides, PET-MRI can also provide information on angiogenesis and metabolic activity for research purposes. Discussion: The use of PET-MRI in the diagnosis and treatment of HNSCC has several advantages. Firstly, the combination of PET and MRI provides high-quality images with high spatial resolution and superior contrast resolution, thereby enabling more accurate delineation of GTV. Moreover, PET-MRI can help in the early detection of radiotherapy response and more accurate monitoring of treatment efficacy. Also, PET-MRI can provide additional functional information such as metabolic activity and angiogenesis, helping in tumor characterization and treatment evaluation. Conclusion: PET-MRI is a valuable imaging technology that can provide more accurate GTV delineation, better monitoring of radiotherapy response, and additional functional information in HNSCC. The application of PET-MRI in oncology is promising and has potential for future clinical applications. The incorporation of PET-MRI with radiotherapy can improve treatment planning, management, and assessment of therapeutic outcomes. Further studies are warranted to evaluate the long-term clinical impact of PET-MRI technology in HNSCC.
