匹多莫德联合川芎嗪治疗小儿支气管哮喘的临床疗效观察.pdf.pdf

匹多莫德联合川芎嗪治疗小儿支气管哮喘的临床疗效观察
刘录*,赵金凤(德令哈市中医院,青海德令哈 087100)
中图分类号 R756;R544 文献标志码 A 文章编号 1001-0408(2013)23-2189-03
DOI .1001-
摘要目的:观察匹多莫德联合川芎嗪治疗小儿支气管哮喘的临床疗效。方法:将我院收治的 80 例支气管哮喘患儿随机均分
成两组。试验组在常规治疗的基础上给予匹多莫德联合川芎嗪联合治疗(匹多莫德分散片,≥10 岁,每次 800 mg,每天 2 次;<10
岁,每次400 mg,每天2次,口服;川穹嗪注射液,≥10岁,每次80 mg,每天1次;<10岁,每次50 mg,每天1次,缓慢静脉滴注;对照
组在常规治疗的基础上给予布地奈德气雾剂(吸入,每次 100 μg,早晚各 1 次,吸入后漱口)。两组均以 7 d 为 1 个疗程,连续 3 个疗
程。评定患儿呼气峰流速值(PEF)、血氧饱和度、1 s 用力呼气容积/用力肺活量(FEV1/FVC)、哮喘起效时间、总有效率和药品不良
反应。结果:与对照组比较,治疗后试验组 PEF、血氧饱和度、FEV1/FVC、哮喘起效时间和总有效率均显著改善(P<)。治疗
组和对照组均出现较轻不良反应。结论:匹多莫德联合川芎嗪治疗中度儿童支气管哮喘有较好的临床疗效。
关键词匹多莫德;川芎嗪;支气管哮喘;儿童
Clinical Efficacy Observation of bined with Ligustrazine in the Treatment of Children with
Bronchial Asthma
LIU Lu,ZHAO Jin-feng(Delingha Hospital of TCM,Qinghai Delingha 087100,China)
ABSTRACT OBJECTIVE:To observe clinical efficacy of bined with ligustrazine in the treatment of children with
bronchial asthma. METHODS:80 children with bronchial asthma in our hospital were randomly divided into 2 groups;40 patients
in trial group were given pidotimod and ligustrazine on the basis of conventional treatment(pidotimod,>10 years old,twice a
day,800 mg each time;<10 years old,twice a day,400 mg each time,a treatment course lasting for 7 days,receiving 3 treatment
courses);Tetramethylpyrazine hydrochloride and sodium chloride injection,≥10 years old,80 m