麻疹(英文).ppt

麻疹
MEASLES
重庆医科大学儿童医院
DIVISION OF INFECTIOUS DISEASE AND GASTROENTEROLOGY
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MEASLES
Key points
DIVISION OF INFECTIOUS DISEASE AND GASTROENTEROLOGY
Acute respiratory infectious disease
caused by measles virus
clinical feature: Fever, Cough, Runny
nose, Conjunctivitis, Exanthem
Specific sign: Koplik’s Spots
(a kind of enanthem )
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DIVISION OF INFECTIOUS DISEASE AND GASTROENTEROLOGY
Classification: A RNA virus
Genus: morbillivirus
Family: paramyxoviridae
Serotype: Only one
Location: Nasopharyngeal secretions,
Blood, Urine of patients
Pathogen
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Pathogen
DIVISION OF INFECTIOUS DISEASE AND GASTROENTEROLOGY
measles virus
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DIVISION OF INFECTIOUS DISEASE AND GASTROENTEROLOGY
Epidemiology
Infectious sources:Measles patients in acute stage
Routes of transmission: Droplet spray
Population susceptibility:
features:
It is susceptible to all the people without infection or inoculation.
The age of peak incidence was 6 months to 5 years old.
The incidence of baby under 6m is lower.
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DIVISION OF INFECTIOUS DISEASE AND GASTROENTEROLOGY
Routes of transmission
Epidemiology
Droplet spray
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DIVISION OF INFECTIOUS DISEASE AND GASTROENTEROLOGY
Prior to the use of ine
After the use of ine
Morbidity (1/100000)
Major epidemics: 500-1000
Mild epidemics: 400
in 1990
Peak season
In winter and spring
In any time of a year
Epidemic cycle
Major epidemics appear by
2-4 yr intervals
Epidemic cycle disappeared, Sporadic cases increased
Age
6m-5y (98%<10y)
Below 6m and above 5y
Clinical manifestations
Typical cases
severe manifestations
plications
high mortality
Atypical cases
mild manifestations
plications
rarely death
Epidemiology
Epidemic Features
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DIVISION OF INFECTIOUS DISEASE AND GASTROENTEROLOGY
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Measles ine Inoculation in whole China (1968)
Epidemiology
Measles cases of in-patients in CHCUMS
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