医学免疫——抗体.ppt

05 Antigen
serum
bacteriotoxin
Precipitation reaction
antibody
antigen
antigen,Ag:
指能刺激机体T淋巴细胞和B淋巴细胞产生细胞和体液免疫应答,并能与相应的免疫应答产物(效应T/B淋巴细胞或抗体)在体内外发生特异性结合的物质.
- Substance that can be recognized by T lymphocytes and B lymphocytes and induce a humoral and/or cellular immune response,and bine specifically with the final products of the above responses (effector T lymphocytes and/or B lymphocytes and/or antibodies).
antigen
识别
immune response
清除
T、B
Effector T/B、antibody
specifically
specifically
Property of Antigen
免疫原性(immunogenicity):
指能刺激机体T淋巴细胞和B淋巴细胞
产生细胞和体液免疫应答的能力
抗原性(antigenicity)/反应原性(immunoreactivity):
能与相应的免疫应答产物(效应T/B淋巴细胞或抗体)在体内外发生特异性结合的能力
Property
Immunogenicity is the ability to induce a humoral and/or cellular immune response.
B cells + antigen  effector B cells + memory B cells

(plasma cellsantibody)
T cells + antigen  effector T cells + memory T cells

(. CTLs, Ths)
Property
Antigenicity is the ability bine specifically with the final products of the immune responses (effector T lymphocytes and/or B lymphocytes and/or antibodies).
半抗原(hapten):
只有抗原性的物质,但单独没有免疫原性的物质.
:have the property of antigenicity, but they alone lack immunogenicity. (Some small molecules)
载体(carrier):与半抗原结合,赋予半抗原 免疫原性(构成完全抗原)的物质