先天性甲状腺功能减退 课件.ppt

CONGENITAL HYPOTHYROIDISM
5th Year Intern- Amila Kannangara
1
Clinical scenario..
A pregnant mother with her es to see you. She is in her third trimester. Both of them are lawyers. They have recently heard about congenital hypothyroidism in Television and wants to discuss with you how to know if their unborn child is affected.
How will you advice them ?
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Content…
is congenital Hypothyroidism?
behind CH?
and symptoms of CH?
to diagnose CH?
CH inherited?
to test for CH?
of CH?
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What is Congenital Hypothyroidism?
Is a state of inadequate thyroid hormone production in newborn infants.
Babies who do not have enough thyroid hormone are often slow to grow, are sluggish, and have learning delays and other specific health problems.
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What are the causes for this condition?
1. Missing or misplaced thyroid gland
Most babies with CH are missing their thyroid gland or have a thyroid that did not develop properly.  In some cases, the thyroid gland may be smaller than usual or may not be located in the correct place. In some children with CH, the thyroid gland may instead be under the tongue or on the side of the neck.
2. Hereditary causes
Children with the inherited type of CH do not make enough thyroid hormone even though their thyroid gland appears normal in size and shape.
3. Maternal iodine deficiency
4. Maternal thyroid condition and medications
5. Multiple births
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what problems occur?
. Poor feeding and poor suck
. Low activity level
. Fewer bowel movements or constipation
. Swelling around the eyes
. Cool, pale, dry skin
. the fontanel that closes late
1. Jaundice
2. Hypotonia
3. Umbilical hernia
4. Large swollen tongue
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If left untreated
Coarse, swollen facial features
Breathing problems
Hoarse-sounding cry
Delayed milestones (sitting, crawling, walking, talking)
Wide, short hands
Poor weight gain and growth
Goiter (enlarged thyroid gland causing a lump in the neck)
Anemia
Slow