小肠间质瘤46例临床特点及治疗.doc

小肠间质瘤46例临床特点及治疗
作者:林克荣,刘建强,张志坚
【Abstract】AIM: To explore the clinical characteristics and diagnosis and therapeutic method of gastrointestinal stromal tumors of the small intestine. METHODS: Clinical data of 46 cases of gastrointestinal stromal tumors of the small intestine admitted 199206/200606 were analyzed retrospectively. The diagnosis was confirmed pathologically for all cases. RESULTS: Gastrointestinal stromal tumors of the small intestine attacked both male and female, with the male to female ratio as ∶ age of the patients ranged from 19 to 80 (average 53) years. The age stage with the highest occurrence rate located at 45-60 years. The major clinical signs included: abdomen pain, abdomen mass, anaemia and small bowel obstruction. The gastrointestinal stromal tumors of the small intestine had predilection in the jejunum and duodenum. The detection rate could be enhanced by PETCT. The most effective therapy was operation removal of the tumors. Glivec might be helpful for patients who had palliative operation or in preventing recurrence. Reoperation could prolong the patients survival, who had local recurrence or distant metastasis. CONCLUSION: The clinical manifestations of gastrointestinal
stromal tumors of the small intestine are nonspecific. The detection rate can be improved by rational auxiliary examinations. The most effective therapy is operatio