应用咪达唑仑与右美托咪定的镇静效果比较.doc

应用咪达哇仑与右美托咪定的镇静效果比较
田莉(四川省达州市中心医院重症医学科635000)
【摘要】目的探究重症监护室中应用咪达唑仑与右美托咪定的镇静效果。
方法将我院ICU收治的100例行机械通气患者,随机分成A、B两组,每组50 例,A组使用咪达唑仑镇静,B组使用右美托咪定镇静,比较两组患者的镇静效果。结果A组患者达镇静满意时间显著短于B组患者(P<),而A组的不良反应发生率、停药后唤醒所需时间均显著高于B组(P均<); A组患者的镇静满意率显著低于B组(P<)。
结论右美托咪定应用于重症监护室患者起效较慢,但唤醒时间短、不良反应发生率低、镇静满意度高。
【关键词】右美托咪定;咪达唑仑;镇静效果【中图分类号】R2【文献标
号】A【文章编号】2095-9753 (2016) 5-0001-02[Abstract] Objective To explore
midazolam with dexmedetomidine sedation anesthesia in icu. Methods in ICU of our
hospital weretreated 100 cases of patients with mechanical ventilation were
randomly divided into two groups: group A and group B, 50 cases ineach group,
group a used midazolam midazolam sedation, group B with dexmedetomidine
sedation, compared two groups of patients withsedative effect. Results in group A,
patients, satisfactory sedation time was significantly shorter in patients in group B (P < ),and a group of incidence rate of adverse reaction and drug withdrawal after wake time were significantly higher than that in group B (P< ); the
sedation satisfaction of patients in group A were rate was significantly lower than
that in group B (P < ). Conclusiondexmedetomidine used in ICU patients with
slow onset, but wake up time is short, the adverse reaction rate is low, sedation
degreehigh.[keyword] dexmedetomidine; midazolam; sedation
为了减轻重症监护室的患者对伤害性刺激产生的应激反应,往往需要