实验生理科学研究性试验论文-芦荟.doc

芦荟汁液对肠蠕动的影响及机制
[摘要] 目的观察芦荟汁液对家兔离体小肠的蠕动,初步探讨其对小肠蠕动影响的机制方法通过建立家兔离体小肠实验,观察肠蠕动频率和幅度的变化结果加入芦荟后,肠蠕动的频率加快,幅度加大;加入阿托品后,肠蠕动频率减慢,幅度减小;加入阿托品和芦荟后,肠蠕动频率加快,幅度减小结论芦荟促进肠蠕动的机制可能也是激动肠粘膜上的M受体,但也不排除可能作用于别的受体。
[关键词] 芦荟肠蠕动频率幅度阿托品
[Abstract] Objective To observe(study)the in vitro effect of aloe Vera extract on the peristalsis of a piece of small intestine from a rabbit,primarily exploring its impact on the mechanism of peristalsis of the small bowel. Methods Through the establishment of in vitro experiments of the small intestine of the rabbit, observe changes in frequency of peristalsis and changes in margin (extent) of peristalsis . Results After the addition of aloe extract,the frequency of bowel movement speeds up,margin of peristalsis also increases;after adding atropine,the frequency of bowel movement slows down,the margin (extent) of bowel movement decreases;after adding atropine and aloe extract;the frequency of bowel movement speeds up,the margin (extent) of bowel movement decreases. Conclusion Aloe Vera extract stimulates the mechanism of peristalsis can be because it activates the M receptors of the Intestinal mucosa but it does not rule out the fact that it can also act on other receptors.
[Key words] Aloe Peristalsis Frequency margin(extent) Atropine
芦荟能有效加强小鼠肠蠕动和减少肠壁重吸收水分功能,且作用温和,起到治疗便秘的作用【1】,芦荟中含有蒽醌类化合物,其包括芦荟素、高那特芦荟素、大黄素、芦荟大黄素、大黄酚、大黄酸等【2】,芦荟大黄素、大黄素能促进肠蠕动,其机制主要是直接作用于肠道的平滑肌Ca2+通道,促