4软骨和骨.ppt

组织胚胎学课件 七年制英文医学班专用
中国医科大学
基础医学院
组胚—英文教学组
Chapter 4  Cartilage and Bone
1. Cartilage:
organ=Cartilage tissue+perichondrium
1)      structure of cartilage tissue
---cell: chondrocyte
---cartilage matrix
①     chondrocyte:
---Structure: LM
embedded in cartilage
lacuna
peripheral cells:
--small and immature
--single and flattened
central cell:
--large and mature,
--round and in group of 2-8 cells
--small and round nucleus
--basophilic cytoplasm
--EM: rich in RER and plex
*isogenous group: several cells locates in one lacuna, which are derived from a single(same) parent cell
②     Cartilage matrix
---ground substance:
proteoglycan:
--same to loose CT
--there are more chondroitin sulfate distributed at the periphery of cartilage lacuna---called as cartilage capsule(basophilic)
chondronectin
water
---fiber: type and number of fiber depends on the type of cartilage
2) Classification: according to the fiber
Hyaline cartilage:
less collagenous fibril←type II collagen
articular surface, rib cartilage, trachea and bronchi
Fibrous cartilage:
large amount of collagenous fiber bundles
cells are small and less
intervertebral disc, symphysis pubis
Elastic cartilage:
large amount of elastic fiber
external ear, epiglottis