躯体化障碍患者神经认知功能比较.doc

躯体化障碍患者神经认知功能比较【摘要】目的:探讨躯体化障碍患者神经认知功能障碍的特点。方法:对60例符合ICD-10躯体化障碍诊断标准的患者给予药物治疗8周,在治疗前、后给予威斯康星卡片分类测验(WCST)、持续操作测验(CPT),同时测验50例正常人作为对照组。患者组的测验结果进行自身前后比较、并分别与正常对照组进行组间比较。结果:患者组治疗前、后WCST的总应答数、完成分类数、持续性错误数、非持续性错误数自身比较,差异有统计学意义(P<~)。患者组治疗前WCST的总应答数、完成分类数、持续性错误数、非持续性错误数与正常对照组组间比较,差异有统计学意义(P<~),治疗后与正常对照组组间比较,差异无统计学意义(P>)。患者组治疗前、后CPT得分比较,在无干扰时差异无统计学意义(P>),有干扰时差异有统计学意义(P<)。患者组治疗前CPT得分与正常对照组组间比较,在无干扰时差异无统计学意义(P>),有干扰时差异有统计学意义(P<),治疗后与正常对照组比较,差异无统计学意义(P>)。结论:躯体化障碍患者存在神经认知功能障碍,但经过治疗可以改善。【关键词】躯体化障碍;神经认知功能;威斯康星卡片分类测验;parisonofneurocognitivefunctioninpatientswithsomatizationdisorder〔Abstract〕Objective::sixtysomatizationdisorderpatientswhomettheICD-10weretreatedfor8weeks,theyweremeasuredwithWisconsinCardSortingTest(WCST)andContinuousperformanceTest(CPT),:Thesignificantdifferenceinthetotaltrials,pletedclassification,preservativeerrors,nor-preservativeerrorsofWCSTwereobservedbetweembeforeandaftertherapyofpatientsgroup(P<~).Andthesameresultswasalsofoundbetweenpatientsgroupbefortherapyandcontrolgroup(p<).Andnosignificantdifferencewasalsofoundbetweenpatientsgroupaftertherapyandcontrolgroup(p>).ComparedtheCPTscoresbetwe