伊见沙坦治疗高血压病的临床研究英文缩写及中英文对照ABP Ambulatorybloodpressure 动态血压ATl angiotensinIItypelreceptor血管紧张素II1型受体AngⅡ Angiotensin II 血管紧张素IIACEl angiotensinconverting 血管紧张素转换酶抑制enzymeinhibitors 剂bpm beatperminute 每分钟跳动次数CBP Clinicbloodpressure 诊室血压DBP Diastolicbloodpressure 舒张压ECG electrocardiogram 心电图EH Essentialhypertension 原发性高血压HR Heartrate 心率IR Insulinresistance 胰岛素抵抗RAS Renin—angiotensinsystem 肾素一血管紧张素系统RAAS - 肾素一血管紧张素一醛固aldosterone system 酮系统SeDSP seateddiastolicblood 坐位舒张压pressureSBP Systolicbloodpressure 收缩压T:P troughtopeakratio 谷/峰比值硕士学位论文 伊贝沙坦治疗高血压病的临床研究国产伊贝沙坦治疗高血压病的临床研究中文摘要1、目的评价国产伊贝沙坦治疗高血压病的降压疗效和安全性。2、方法采用随机、对照法将126例高血压病(EH)患者分为国产伊贝沙坦组(64例,150mg/d)和苯那普利组(62例,10mg/d),治疗4周。以诊室血压(CBP)和24小时动态血压(ABP)为指标观察国产伊贝沙坦的降压效果,及其对血糖、血脂和肝肾功能的影响。3、结果与治疗前相比,国产伊贝沙坦组和苯那普利组CBP均明显降低(P<),但心率无明显变化(P>)。二组间比较,降压幅度无显著差异(P>)。%、%;%、%,组间比较均无显著性差异(P>)。24小时ABP结果显示:二种药物均有明显降低ABP的效果(P<),不影响血压昼夜节律,谷/峰比值均大于55%。治疗前后的血压曲线均明显分离,呈螺硕士学位论文 伊哭沙遵治痃藩痊L疆瘫翡貉藤研究旋平行状态。二种药物对血糖、赢脂、肝肾功能及电解质无明显影貔(p>O。05)。不艇反瘟发生率謦产伊受沙毽篷尧12,5%,%fP>)。4、结论国产伊贝沙坦可有效、安全地降低高m压病患者觑压,其疗效和苯郡普剥襁议,不是反应发生率秘燕。5、关键词豫发憷藩鑫歪伊灵沙毽苯霈善剽动态蛊压{漆庶骚究硕士学位论文 第7聪 共50页伊贝沙坦治疗高血压病的临床研究ClinicalStudyoflrbesartan intheTreatmentofHypertensionAbstractobjective:Toevaluate the efficacy and safety ofhomemade irbersartan in hypertensive patientSMethods:Onehundred and twenty Six patientS withmild to moderate essential hypertension were randomizedinto irbesartan(n=64)andbenazepril(n=62)groupsbydouble-blind method and treated with irbesartan(150mg/d)andbenazepril(10mg/d)respectivelyfor clinical blood pressure(CBP)andambulatoryblood pressure monitoring(ABP)wereperformed pare the efficacy of the two influencesof iz—besartan and benazepril on blood glucose,lipidand function of liver and kidney were also investigatedResults:After four weeks monotherapy,the clinicalblood pressure decreased significantly in bothirbesartan and benazepril groups(P<).But the he
