排毒降脂胶囊治疗非酒精性脂肪肝临床观察.doc

排毒降脂胶囊治疗非酒精性脂肪肝临床观察作者:赵晓琴,张霖【关键词】非酒精性脂肪肝;,,排毒降脂胶囊摘要:目的观察排毒降脂胶囊治疗非酒精性脂肪肝的临床疗效。方法按诊断标准选取非酒精性脂肪肝患者112例,随机分成治疗纟I[与対照组。治疗组69例,采用排毒降脂胶囊(白术、大黄、泽泻、丹参、山楂、生首乌等)治疗,对照组43例用东宝川漆治疗。疗程为3个月。%,并在降低血脂、改善肝功能方而均与对照组有显著差异(P<)«结论排毒降脂胶囊治疗非酒精性脂肪肝具较好疗效,有临床应用价值。关键词:非酒精性脂肪肝;排毒降脂胶囊ClinicalObservationonPDJZCapsuleinTreatingNonalcoholicFattyLiverDiseaseAbstract:ObjectiveToinvestigatethecurativeeffectofPaidujiangzhi(PDJZ)capsuleontreatingNonalcoholicfattyliverdisease(NAFLD).Methods112casesofNAFLDwererandomlydividedintothetreatedgroupandcontrolgroup,theformerwithPDJZcapsule(twicedaily,3tabletseachtime),thelaterwithDongbaogantaitablets(twicedaily,2pillseachtime).reatmentperiod,,levelsofserumTG,TC,andthefunctionofliverwerechecked,%intreatedgroupwasobviouslybetterthanthatincontrolgioup(P<);thelevelsofTGTC,ALT,paredwithcontrolgroup(P<).:Nonalcoholicfattyliverdisease(NAFLD);PDJZcapsule非酒精性脂肪肝(Nonalcoholicfattyliverdisease,NAFLD)是多种原因所导致的肝内脂肪过度沉积。随着肥胖、糖尿病发病率的增高,非酒精性脂肪肝病人也有逐年增多的趋势。估计普通人群中NAFLD发生率20%(5%〜39%),NAFLD发牛率2%~3%(%〜%),它最终可发展为肝硬化,其病理学改变类似酒粘性肝病,但发生于无嗜酒的患者。丨I前对NAFLD的发病机理耒完全明确,尚无公认的治疗药物[2]。我院排毒降脂胶囊采用纯中药制剂,在治疗NAFLD中取得了较好的疗效。现将69例排毒降脂胶囊治疗NAFLD临床观察报道如下。,全部病人均经实验室检查排除乙型、内型肝炎。无饮酒史。随机分为两组。治疗纽69例,男48例,女21例;年龄30〜65岁;合并髙血压病者5例,2型糖尿病1例。对照组