伊贝沙坦和西拉普利降压效果的比较【关键词】高血压,关键词:伊贝沙坦;西拉普利;高血压摘要:目的比较血管紧张素?受体拮抗剂伊贝沙坦和血管紧张素转化酶抑制剂西拉普利对轻、、中度高血压患者~经2wk洗脱期后~分为伊贝沙坦组和西拉普利组~每日分别服用伊贝沙坦150,,~、心率变化~对比服药前后超声心动图各指标~~%~%~两组比较无显著性差异,P>,.与本组服药前比较~两组血压均有显著性下降,P<,~伊贝沙坦组较西拉普利组下降更为明显,P<,.超声心动图二尖瓣舒张早期血流峰值,E,~二尖瓣舒张晚期血流峰值,A,~及E/A比值~与本组服药前比较均有显著差异,P<,~两组间无显著性差异,P>,.实验室检查及心电图无显著性改变,P>,.结论伊贝沙坦每日150,300mg治疗轻、中度原发性高血压~具有良好的降压作用~:irbesartan;cilazapril;hypertensionAbstract:pareefficacyandtheef--edwithirbesartan150,,~sittingbloodpressure~heartrate~echocardiographyandlaboratoryexaminationofthepatientswereobservedatbaselineandpost---ment~%ofpatientsinirbesar-%incilazaprilgroup,P>,.Thede-creaseofsittingbloodpressurewassignificantinbothofthetwogroups,P<,~irbesartangroupwasmoresignifi-cant,P<,.Intwogroups~atiralpeakfillingvelocity,A,wasalldecreased,P<,~earlypeakfillingvelocity,E,andE/Aradiowereincreased,P<,;therewerenostatisticaldifferencesbetweenirbesartanandcila
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