3D-TomosynthesisRichard MelpignanoBME-18111 February 2013Breast Cancer?monly diagnosed cancer and second leading cause of death in women in the ?220,000 diagnosed cases every year in ?40,000 deaths every year in ?About one in eight women will be diagnosed with breast cancer at some point in their lifeTraditional Mammography?Has been around for over 100 years?Uses X-rays to spot tumors in the breasts?Mammograms can help reduce death from breast cancer by 15% by spotting tumors early in developmentProblems?Often unclear detection method?High amounts of over-diagnosis and under-diagnosis?This leads to multiple unnecessary screenings and more exposure to X-ray radiation?Limited 2-dimensional image leaves about 10% of cancers undetected?Denser breast tissue is difficult to read in some patientsNew Detection Method?Mass General Breast Imaging teams began creating and designing a new breast cancer detection method over 10 years ago?Their method, Tomosynthesis, was approved by the FDA in February 2011 and has started to spread throughout the ?In Washington, alone, over 35,000 procedures have been performed since August 2011?Utilizes low-level X-rays to produce multiple images of the breast, layer by layer, using a swinging camera?This layering of images makes it simpler to detect normal breast structures (milk ducts, lobules, fatty tissues, etc.) from cancerous ones?X-rays are converted into limited 3-dimensional digital images for radiologists to puter Aided Detection (CAD) assists in spotting regions where cancer seems to be present?Dense tissue is more easily examined through Tomography than traditional MammographyTomosynthesisMammography vsTomosynthesisNo lesion detectedLesion detectedTomosynthesis (cont.)?Increases detection of Invasive breast cancers by 40% parison to 2D mammography?Total cancer detection increased from patients per thousand to patients per thousand (a 27% increase)?False-positive readings reduced by 15%?Uncertain readings and
