盖诺联合顺铂治疗蒽环类耐药乳腺癌临床观察.doc

盖诺联合顺铂治疗蒽环类耐药乳腺癌临床观察.doc盖诺联合顺钳治疗蔥环类耐药乳腺癌临床观察夏月琴,何续逊盐城市肿瘤医院肿瘤内科,江苏盐城224002[摘耍]冃的探讨对蔥环类耐药乳腺癌的有效化疗方案。方法对23例蔥环类治疗过的转移性乳腺癌给予国产异长春花碱(盖诺NVB)加顺釦(DDP)化疗。%,%,%%,%,%,淋巴结、胸膜、骨、%、%、%>0,心包100%o剂量限制性毒性是骨髓抑制。结论NVB联合DDP可作为蔥环类耐药乳腺癌冇效的二线治疗方案。[关键词]乳腺肿瘤/药物疗法;长春碱/投药和剂量;顺钳/投药和剂量;抗生素类,蔥环;抗药性,肿瘤[中图分类号] [文献标识码]A [文章编号]03-01-binationChemotherapywithNVBandDDPforMetastaticBreastCancerResistanttoAnthracyclineXiaYueqin, HeXuxunDepartmentofMedicalOncology,YanchengTumorHospital,Yancheng224003,ChinaAbstract:(NVB)25mg/m2,daylandday8andCisplatin(DDP)30mg/m2day2・%(11achievedpartialresponse),%,%.%,%,%,%,%,%,liver0zpericardia100%,・limitingtoxicitywasneutropenia(%ofpatients).binationofNVBandDDPisaneffectiveregimenassecond-reatmentformetastaticbreastcancerpatientsresistanttoanthraxcyclineKeywords:breas