adm包扎治疗ⅱ度烧烫伤创面临床效果的观察.doc

ADM包扎治疗Ⅱ度烧烫伤创面临床效果的观察【摘要】目的探讨ADM(异种脱细胞真皮基质)包扎治疗Ⅱ°烧烫伤创面的临床效果。方法随机采用异种脱细胞真皮基质包扎治疗(治疗组)和使用磺胺嘧啶银乳膏包扎治疗(对照组)的Ⅱ°烧烫伤创面各50例患者。比较两组在换药后疼痛、换药次数、预后瘢痕增生等方面的差异。结果治疗组0-Ⅰ级疼痛入院时22例(44%),治疗后48例(96%),差异具有统计学意义(p<);对照组0-Ⅰ级疼痛入院时23例(46%),治疗后22例(44%),差异无统计学意义(p>)。两组治疗后0-Ⅰ级疼痛率比较,差异有明显统计学意义(p<)。治疗组患者创面愈合后比对照组皮肤颜色更浅、弹性更好。半年后创面疤痕形成有明显差异(p<)。结论:异种脱细胞真皮基质用于治疗Ⅱ°烧烫伤创面具有止痛快、促进创面愈合,减少瘢痕增生,减轻患者痛苦,减少医生劳动量等优点。ADM是一种较理想的内层包扎敷料。【关键词】ADM包扎,Ⅱ度烧烫伤,临床效果ClinicaleffectevaluationofADMdressingonthewoundhealingofseconddegreeburnAbstractObjectiveToinvestigatetheclinicaleffectofADM(HeterogeneousAcellulardermalmatrix)(treatmentgroup)andthetreatmentgroup(controlgroup)withtheuseoftheHeterogeneousAcellulardermalmatrix(treatmentgroup).Thedifferencesofthetwogroupsinthechangeofthepain,thenumberofdressingchange,(44%),aftertreatmentof48cases(96%),thedifferenceisstatisticallysignificant(P<);group0classIpainonadmissioncontrol23cases(46%),aftertreatmentin22cases(44%),thedifferencewasnotstatisticallysignificant(P>).Inthetwogroupsaftertreatment,therewassignificantdifferencein0-gradepainrate(p<).,thereweresignificantdifferencesinwoundscarformation(p<)