南阳理工学院本科生毕业设计(论文) 学院( 部): 生物与化学工程学院专业: 生物工程姓名: 方帅指导老师: 肖连冬(教授) 完成日期 2014 年4月南阳理工学院本科生毕业设计(论文) 年产 5 万吨α- 淀粉酶工厂发酵车间设计 The D esign for A lpha A mylase F ermentation W orkshop with 50000 tons Annual Production 总计: 毕业设计(论文) 33页表格: 5个插图:3幅南阳理工学院本科毕业设计(论文) 年产 5 万吨α- 淀粉酶工厂发酵车间设计 The D esign for A lpha A mylase F ermentation W orkshop with 50000 tons Annual Production 学院(部):生物与化学工程学院专业: 生物工程学生姓名: 方帅学号: 105010540041 指导教师(职称): 肖连冬(教授) 评阅教师: 完成日期: 2014 年4月 i 年产 5 万吨α- 淀粉酶工厂发酵车间设计生物工程专业方帅[摘要] :α-淀粉酶广泛分布于动物、植物和微生物中,能水解淀粉产生糊精、麦芽糖、低聚糖和葡萄糖等,是工业生产中应用最为广泛的酶制剂之一。目前, α-淀粉酶已广泛应用于变性淀粉及淀粉糖、焙烤工业、啤酒酿造、酒精工业、发酵以及纺织等许多行业。本次设计的淀粉酶发酵工厂年产量为 50000 吨,以枯草芽孢杆菌( Bacillus subtilis ) BF -7658 为生产菌种,以玉米粉为碳源,以豆饼为氮源,采用液体深层发酵法发酵,以此为基础进行设计,确定了生产工艺流程,进行了物料衡算和热量衡算,并计算了主要设备的尺寸。[ 关键词] :α-淀粉酶;生产过程设计;深层发酵法 ii The D esign for alpha A mylase F ermentation W orkshop with 50000 tons Annual Production Biological engineering FANG Shuai Abstract :A lpha amylase widely distributed in animals, plants and microbes, hydrolysis can produce dextrin, maltose starch, harides and glucose and soon, it is the most widely used in industrial production ofone of the enzyme preparation. At present, the alpha amylase has been widely used in modified starch and starch sugar, baking industry, beer brewing, alcohol industry, fermentation and textile and the many industries. The design of the fermentation plant amylase, respectively, with corn flour for carbon sources, to soybean cake as nitrogen source, with BF-7658 Bacillus subtilis strains for production, the deep fermentation, by salting-out extraction technology method, with the annual production capacity of50000 tons of amylase, 167 tons per day. At the same time make the production process flow diagram, the material balance calculations and heat balance calculations, the design and the size of the cans of fermentation tank seeds. Keywords: alpha amylase; Production process design; Deep fermentatio n i 目录 1 绪论.............................................................................
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