琥珀酸美托洛尔治疗慢性心力衰竭效果分[摘要]目的:研究琥珀酸美托洛尔缓释片对慢性充血性心力衰竭(CHF)患者的心功能改善情况。方法:将60例患者随机分为治疗组(30例)与对照组(30例),治疗组患者在常规用药的基础上,应用琥珀酸美托洛尔缓释片进行治疗,观察对比两组治疗6个月前后的左室舒张末期内径(LVEDD)、左室收缩末期内径(LVESD)、左心室射血分数(LVEF)等心功能指标和愈后情况。结果:两组治疗前比较LVEDD、LVESD、LVEF及B型钠尿肽(BNP)参数值水平比较,差异无统计学意义(P>);治疗后,两组的LVEDD、LVEF及BNP参数值比较,差异有统计学意义(P<),证明琥珀酸美托洛尔能改善患者心功能指标。结论:琥珀酸美托洛尔能显著改善慢性充血性心力衰竭患者的心脏功能。[关键词]琥珀酸美托洛尔;慢性充血性心力衰竭;效果[中图分类号][文献标识码]A[文章编号]1673-7210(2011)11(c)-080-inateinthetreatmentofchronicheartfailureSHIHongDepartmentofCardiology,GulouHospitalAffiliatedtoNanjingUniversity,JiangsuProvince,Nanjing210000,China[Abstract]Objective:TostudythecardiacfunctionimprovementofMetoprololsustained-ongestiveheartfailure(CHF).Methods:60patientswererandomlydividedintotreatmentgroup(30cases)andcontrolgroup(30cases).ThetreatmentgroupwasgivenMetoprololsustained-(LVEDD),leftventricularendsystolicdimension(LVEF):TheLVEDD,LVESD,LVEF,BNPlevelparametersofthetwogroupsbeforetreatmenthadnosignificantdifference(P>);thedifferencesofLVEDD,LVEFandBNPparametersaftertreatmentbetweenthetwogroupswerestatisticallysignificant(P<),:inatesustained-releasetabletscancontroltheventricularrateeffectively,improveheartfunctionsignificantlyandalsoreverseleftvent
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