读书报告.ppt

Investigation of the State and Dynamics of Water in Hydrogels of Cellulose Ethers by 1H NMR Spectroscopy
林业工程
20**********
--AAPS PharmSciTech 2002
Saša Baumgartner1, Gojmir Lahajnar2, Ana Sepe2, and Julijana Kristl1
1University of Ljubljana, Faculty of Pharmacy,Aškerčeva 7,
SI-1000 Ljubljana, Slovenia
2Jožef Stefan Institute, Jamova 39, SI-1000 Ljubljana, Slovenia
Submitted: September 13, 2002; Accepted: December 28, 2002
Choose the paper's reason:

To study some knowledge about NMR
Correlation with my research
Controlled release of drugs is becoming one of the more dynamic fields of pharmaceutical research. It shows numerous advantages including fewer side effects and better patient compliance.
Hydrogels are 3-dimensional complex systems composed of tangled polymer network structures and incorporated water.
NMR spectroscopy is a powerful technique for detailed studies of the structure, mobility, and hydration properties of various polymeric systems
BACKGROUND
在磁共振成象技术中，由停止发射无线电波至原子核恢复原来平衡状态的间隔时间，称弛豫时间。弛豫时间有纵向、横向两种。前者称自旋—晶格弛豫时间，后者称自旋—自旋弛豫时间。
spin-lattice relaxation time :也称纵向弛豫时间，是处于高能态的核自旋体系与周围的环境之间的能量交换过程，达到热平衡状态所需的时间，用半衰期T1表示。
Nouns explanation
spin-spin relaxation time :自旋-自旋弛豫时间，高能态的自旋核与同类的低能态核之间能量的转移时间。
HPC:Hydroxypropylcellulose-羟丙基纤维
HPMC:hydroxypropyl methyl cellulose --羟丙基甲基纤维素
HEC:羟乙基纤维素
The aim of this work was to study the effect of the type of substituent of the cellulose ethers and the molecular mass on the state and dynamics of water in the respective hydrogels to specify the quantity of adsorbed water on the polymers or, to calculate the average number of water molecules bound to a PRU.
PAPER'S PURPOSE: