心通口服液降低动脉粥样硬化和高脂血症药效学研究更新日期:2011-01-24 点击:张玉芝摘要:心通口服液具有益气养阴、活血化瘀、软坚化痰之功能,多年用于临床治疗冠心病心绞痛,收到了良好的效果。动物试验表明:心通口服液高剂量组、维生素E组、脉安冲剂组,均能使高脂大鼠的CH,TG值降低(P<),心通口服液高剂量组和维生素E组还能使HDL-C值升高(P<)。心通口服液高剂量组与维生素E组能明显降低鹌鹑高血脂模型的CH和TG(P<)使HDC-C值升高,并可降低动脉粥样硬化斑块的发生率。关键词:心通口服液;动脉粥样硬化;高脂血症中图分类号::A文章编号:1008-0805(2000)09-0771-02 The Pharmacological Studies of Xintong Oral Liquid on the Treatment of Atheroscleorsis and Hyperlipemia ZHANG Yu-zhi (Shandong Provincial Institute of Traditional Chinese Medicine and Materia Medica, Jinan 250014, China) Abstract:In the terms of traditional Chinese medicine, Xintong oral liquid can supplement the vital energy and nurish yin, soft the hard lumps and dissipate phlegm and promote blood circulation to disperse blood stasis. It has been being a well effective drug for the treatment of coronary heart disease and angina pectoris in clinic for many years. This paper reports the animal test results of Xintong oral liquid on treating atheroscleorsis and hyperlipemia in which showed that high dosage of Xintong oral liquid, as well as vitamin E and Maian granules, could decrease the CH and TG values of hyperlipemia rats (P<). And similar to vitamin E, it could increase their HDL-C values (P<). Also same as vitamin E, high dosage of Xintongoral liquid could significantly decrease the CH and TG (P<) and increase the HDL-C of hyperlipemia qua