[摘要] 目标 分析联合应用氟桂利嗪和低分子肝素诊疗频发性短暂脑缺血发作的疗效。 方法 选择146例频发性短暂脑缺血发作患者,按诊疗方案不一样分为两组:对照组,给予低分子肝素诊疗,共77例;研究组,在低分子肝素基础上加用氟桂利嗪,共69例。诊疗2周后,分别进行临床疗效及不良反应比较。 结果 和对照组比较,研究组总有效率、显效率显著较高,两组诊疗后全血黏度、全血黏度、血浆黏度、纤维蛋白原含量较诊疗前显著下降,但诊疗后研究组较对照组显著改进。研究组的血细胞降低、皮疹、头痛、肝功效异常等不良反应较对照组差异无统计学意义。 结论 应用氟桂利嗪和低分子肝素诊疗频发性短暂脑缺血发作疗效可靠,不良反应少。 [关键词] 氟桂利嗪;低分子肝素;短暂脑缺血发作;疗效;不良反应 [中图分类号] [文件标识码] A [文章编号] 1673-721007-0060-03 Efficacy of Flunarizine and low molecular weight heparin for the frequency of recurrent transient ischemic attacks WANG Dejun YU Lingling SUN Dongliang The Second Department of Internal Medicine, Tanghai Affiliated Hospital of Hebei Union University, Hebei Province, Tanghai 063200, China [Abstract] Objective To analyze the efficacy of the combination of Flunarizine and low molecular weight heparin for the frequency of recurrent transient ischemic attacks . Methods 146 cases of frequent TIA patients were randomly divided into 2 groups according to the treatment program. 77 patients of control group were given low molecular weight heparin, 69 patients of control group were treated with Flunarizine on the basis of low molecular weight heparin. The clinical efficacy and adverse reactions of two groups after treatment were compared. Results Compared with the control group, the utility and excellence rates of the study group were significantly highe