妊娠中晚期孕妇B族溶血性链球菌感染率及其对母婴结局的影响 [摘要]目的 探討妊娠中晚期孕妇发生B族溶血性链球菌感染的风险及B族溶血性链球菌感染后对母婴结局的影响。方法 采用简单随机抽样法选取2017年3～12月在我院妇产科进行定期孕检并分娩的217例妊娠中晚期孕妇展开研究，均采用胶体金层析法进行B族溶血性链球菌检测，统计B族溶血性链球菌感染发生情况。然后将B族溶血性链球菌感染阳性的22例孕妇作为观察组，B族溶血性链球菌感染阴性的195例孕妇作为对照组。比较两组孕妇的B族溶血性链球菌感染发生率、妊娠结局（胎膜早破、早产、胎儿窘迫发生率）以及新生儿结局（新生儿感染、早产儿、新生儿窒息发生率）。结果 217例孕妇中，有22例感染B族溶血性链球菌，%。≥30岁孕妇的B族溶血性链球菌感染率明显高于<30岁孕妇的感染率，差异有统计学意义（P<）。观察组孕妇的胎膜早破、早产、胎儿窘迫发生率低于对照组，差异有统计学意义（P<）。观察组的新生儿感染发生率高于对照组，新生儿黄疸、早产儿、新生儿窒息发生率低于对照组，差异有统计学意义（P<）。结论 妊娠中晚期孕妇感染B族溶血性链球菌可导致早产、胎膜早破、新生儿感染等不良妊娠结局，需要规范治疗干预，改善妊娠结局。 [关键词]妊娠中晚期;B族溶血性链球菌;感染率;妊娠结局 [中图分类号] [文献标识码] A [文章编号] 1674-4721（2019）6（a）-0161-04 [Abstract] Objective To investigate the infection risk of group B hemolytic streptococcus in middle and late pregnant women and its effect on the maternal and fetal outcomes. Methods By a random simple sampling， 217 women in the middle and late pregnancyfor regular pregnancy tests were enrolled from March to December in 2017 in the department of obstetrics and gynecology in our hospital. The colloidal gold chromatography was used for group B hemolytic streptococcus detection， and the infection rate of group B hemolytic streptococcus was analyzed. After that， 22 pregnant women with positive group B hemolytic streptococcus infection were enrolled as observation group， and the remaining 195 pregnant women with negative group B hemolytic streptococcus infection were as control group. The infection rate of group B hemolytic streptococcus， pregnancy outcomes including incidence of premature rupture of membranes， premature delivery， and fetal distress， and neonatal outcomes including incidence of neonatal infection， premature infant， and neonatal asphyxia in the two groups were compared. Results Twenty-two of the 217 patients were infected with group B hemolytic streptococcus， accounting for %. The infection rate of group B hemolytic streptococcus in ≥30-year-old pregnant women was significantly
