托烷司琼预防含顺铂化疗药物所致恶心、呕吐的临床观察 [摘要]目的：观察托烷司琼预防含顺铂化疗药物所致恶心、呕吐的疗效和不良反应。方法：将入选62例接受含顺铂联合化疗的恶性肿瘤患者，随机分成两组，观察组32例病人于化疗前使用托烷司琼止吐，对照组30例病人使用昂丹司琼。观察两组病人恶心、呕吐的控制情况及不良反应。结果：托烷司琼和昂丹司琼预防化疗后恶心、呕吐的有效率无明显差异（P>）；但完全控制率托烷司琼优于昂丹司琼（P [关键词]托烷司琼；昂丹司琼；化疗；恶心、呕吐 [中图分类号] [文献标识码]A [文章编号]1673-7210（2007）03（c）-014-02 Clinical observation of tropisetron in preventing nausea and vomiting induced by chemotherapeutic drugs including cisplain WANG Jin-cai,ZHENG Ji-hai,LI Xiao-rui (The First Affiliated Hospital of Xinxiang Medical College,Weihui 53100，Chian) [Abstract]Objective:To observe the therapeutic effect and adverse reactions of tropisetron in preventing nausea and vomiting induced by chemotherapeutic drugs including :32 patients with cancer undergoing chemotherapy regimens including cisplain were divided randomly into 2 groups(observative group was given tropisetron before chemotherapy and control group was given ondansetron).The situation of nausea,vomiting and adverse reactions were observed and :There was no significant difference in the total effective rate between tropisetron and ondansetron in preventing nausea and vomiting induced by chemotherapy(P>).Tropisetron was superior to ondansetron in the complete control rate().Conclusion:Tropisetron was safe and effective in preventing nausea and vom
