低频振幅联合功能连接对原发性失眠的研究.pdf

CHINESE JOURNAL OF CT AND MRI, FEB. 2022, , Total
Studyperior frontal gyrus and left triangular
part of the inferior frontal gyrus; ALFF decreased in bilateral middle frontal gyrus and left posterior
【摘要】目的 低频振幅(ALFF)联合功能连接探讨原
cingulate gyrus. In the functional connectivity, the functional connectivity between the right middle
发性失眠患者脑功能及网络改变。方法 64名原发性
失眠患者(患者组)和59名健康对照者(对照组)进行静 temporal gyrus and the left middle occipital gyrus was reduced in the patient group. Those with
息态功能磁共振扫描，然后对两组间的ALFF值以及 increased functional connectivity included: between right supplementary motor area and right medial
ALFF值差异脑区的功能连接进行独立样本t检验分 superior frontal gyrus, right supramarginal gyrus; Between the right medial superior frontal gyrus and
析。结果 患者组ALFF增高的脑区为右侧颞中回、右 the left supplementary motor area extend to the bilateral frontal lobe; Between left triangular part of
侧补充运动区、右侧额上回内侧、左侧额下回三角 the inferior frontal gyrus and the left dorsolateral superior frontal gyrus, the right precuneus, the left
部；ALFF值降低的脑区为双侧额中回、左侧后扣带 middle occipital gyrus, the right inferior parietal angular gyrus; Between the left middle frontal gyrus
回。