中国当代医药 年 月第 卷第 期 ·检验医学· 202定 [中图分类号] [文献标识码] A [文章编号] 1674-4721(2021)7(c)-0182-03 Application effect of four items of liver fiber detection in the diagnosis of liver fibrosis LIU Zhi-ru Department of Laboratory Medicine, Fushun Infectious Disease Hospital, Liaoning Province, Fushun 113015, China [Abstract] Objective To explore the application effect of four items of liver fiber detection in the diagnosis of liver fi- Methods brosis. The clinical data of 400 patients with suspected liver fibrosis in Fushun Infectious Disease Hospital from February 2017 to February 2019 were retrospectively analyzed. A total of 158 patients were selected as the obser- vation group, and they were divided into viral liver cirrhosis, cholasis hepatic cirrhosis, alcoholic cirrhosis, liver cirrho- sis caused by autoimmune liver disease and stasis cirrhosis according to the condition. While 202 patients with non- cirrhosis treated at the same period were selected as the control groups. Hyaluronic acid (HA), laminin (LN), collegen type Ⅳ (CⅣ) and procollagen Ⅲ N-terminal propeptide (PⅢNP) were measured in the two groups, and the diagnostic