单次大剂量丙种球蛋白治疗新生儿ABO溶血病的效果.doc

单次大剂量丙种球蛋白治疗新生儿ABO溶血病的效果
【摘要】 目的 探討单次大剂量丙种球蛋白治疗新生儿ABO溶血病的效果。方法 52例ABO溶血病新生儿作为研究对象, 按照随机数字表分组法分为观察组与对照组, 各26例。对照组患mol/L in the control group, and the difference was statistically significant (P<). After 30 d of treatment, the red blood cell count was (±)×1012/L in the observation group, which was higher than (±)×1012/L in the control group, and the difference was statistically significant (P<). There was no statistically significant difference in jaundice arriving peak time and bilirubin level during peak jaundice between the two groups (P>). There was statistically significant difference in jaundice regression time between the two groups (P<). Conclusion Single large dose of γ-globulin shows remarkable effect in the treatment of ABO hemolytic disease children, and it is worthy of clinical promotion and application. 【Key words】 Single large dose of γ-globulin; Neonatal ABO hemolytic disease; Jaundice
新生儿在出生1个月内称之为新生儿时期[1], 新生儿时期不仅是新生儿生长发育的关键时期, 由于新生儿出生时间短, 机体抵抗力相对较弱, 因此也是新生儿患病高危时期[2]。ABO溶血病是临床中较为常见的新生儿疾病, 是引发新生儿出现黄疸的主要原因[3], 在治疗不及时的情况下, 新生儿极易合并胆红素脑病, 使新生儿产生智力下降、听力下降等后遗症, 严重者将出现脑瘫等严重疾病[4], 对新生儿生活质量带来极大影响, 因此, 要及时对新生儿ABO溶血病进行有效治疗, 有研究表明:大量单剂量丙种球蛋白对治疗ABO溶血病效果显著[5]。基于此, 本次研究针对单次大剂量丙种球蛋白治疗新生儿ABO溶血病的效果展开探讨, 现报告如下。
1 资料与方法
1. 1 一般资料 选取2018年3月1日~2019年3月1日本院收治的52例ABO溶血病新生儿作为研究对象, 按照随机数字表分组法将其分为观察组与对照组, 各26例。观察组中男14例, 女12例;胎龄38~41周