前列安栓治疗慢性前列腺炎临床研究.pdf

汕头大学硕士研究生论文
Abstract

Abstract Objective
To evaluate the efficacy and safety of Prostant in the treatment of chronic prostatitis.
Methods
A randomized, double-blind, positive drug-controlled clinical trial method was applied in
the study. Through clinical symptoms, signs and expressed prostate secretion (EPS) examination,
80 patients with prostatitis were recruited and randomixed into a trial group (60 cases) and a
control group (20 cases). After screening, treatment and follow-up, in the trial group and the
control group, the observation on clinical efficacy and safety were evaluated, such as the clinical
symptoms, signs, EPS examination, the national institute health-chronic prostatits symptom
index (NIH-CPSI) and the blood routine, urine routine, stool routine, the function of liver and
kindney,electrocardiograph examination and the side effects.
Results
After 4-week treatment, For different types of the two groups,the total effective rates were
% in the trial group and % in the control group, the effect of the efficacy of Prostant
was superior to that of wild chrysanthemum suppository(P=).There was significant
difference in clinical symptoms and NIH-CPSI between pre-treatment and post-treatment in the
trial group and the control group (P<). Though there was remarkable difference between
pre-treatment and post-treatment in the white blood cell count in the EPS (P<), not in
difference of two groups (P=). The tolerance to Prostant and wild chrysanthemum
suppository showed no significant difference (P=), and no serious side effects were
recorded.
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汕头大学硕士研究生论文
Conclusion
The Prostant is effective and safe on treating the chronic prostatitis and well deserves to be
mended in clinical practice.
Key words chronic prostatitis; clinical trial; Prostant; the rapeutics













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汕头大学硕士研究生论文
英文缩略词及关键词表

Ber berberine 小檗碱
CAP Chronic a