临床医学研究与实践 2022 年 5 月第 7 卷第 15 期 临床医学 盐酸氨溴索联合含环丝氨酸抗结核方nce for clinical drug selection. Methods A total of 100 patients with multi-drug resistant tuberculosis treated in our hospital from November 2015 to November 2019 were selected as the research objects. The patients were divided into control group and observation group according to random number table method, with 50 cases in each group. The control group was given standardized treatment of multi-drug resistant tuberculosis, and the observation group was given ambroxol hydrochloride combined with containing cycloserine antituberculosis regimen treatment on the basis of the control group. The clinical efficacy, negative conversion of Mycobacterium tuberculosis in sputum, cavity shrinkage and foci absorption, serum indexes and occurrence of adverse reactions were compared between the two groups. Results The total effective rate of treatment in the observation group was %, which was higher than % in the control group, and the difference was statistically significant (P<). After 3 months of treatment, there were no significant differences in negative conversion rate of Mycobacterium tuberculosis in sputum, cavity shrinkage rate and foci absorption rate between the two groups (P>); ater 6, 12 and 2
