布洛芬对急性上呼吸道感染患儿的退热效果.doc

1 布洛芬对急性上呼吸道感染患儿的退热效果【关键词】布洛芬;对乙酰氨基酚;退热;儿童[摘要] 目的:观察布洛芬混悬液的退热效果。方法:选择有高热症状的急性上呼吸道感染患儿 100 例,随机分为两组, 分别用布洛芬混悬液( 56例) 和对乙酰氨基酚口服溶液( 44 例) 治疗,记录首次给药后 、 、 、 、 、 、 和 h 的体温变化。结果: 布洛芬组和对乙酰氨基酚组体温降低 ℃所需的平均时间分别为( 110 ± 78) min 、( 119 ± 82) min , 比例分别为 % 和 % ( )。体温恢复正常时间分别为( 110 ± 76) min 、( 124 ± 78) min ( ) ,比例分别为 % 和 % ( ) 。前 2h 两组体温下降相似,在 、 、 和 h 布洛芬组平均体温下降大于对乙酰氨基酚组,体温正常化维持时间更长。结论:布洛芬退热疗效优于对乙酰氨基酚。[关键词] 布洛芬;对乙酰氨基酚;退热;儿童 Antipyretic effectiveness of ibuprofen suspension in 2 children with acute upper respiratory infection [ Abstract ] Objective:To observe the antipyretic effectiveness of ibuprofen and acetaminophen. Methods: One hundred febrile children, suffered acute upper respiratory infection, were randomized into ibuprofen (56) and acetaminophen (44) groups. Temperature was recorded at , , , , , , , hours after drug administration. Results: The average time for ℃ decrease in the temperature was (110 ± 78) min with ibuprofen versus (119 ± 82) min with acetaminophen. The proportions, respectively, were % and % (). Temperature normalization times were (110 ± 76) min in the ibuprofen pared with (124 ± 78) min in the acetaminophen one (). Temperature normalization rates in the ibuprofen group (%) were significantly higher than the acetaminophen group (6