甲磺酸加替沙星葡萄糖注射液治疗急性细菌性感染48例.doc

甲磺酸加替沙星葡萄糖注射液治疗急性细菌性感染48例.doc甲磺酸加替沙星葡萄糖注射液治疗急性细菌性感染48例
作者:吴寅文爱东吴昌归王汉民简文许国双赵磊石茹【关键词】甲磺酸加替沙星
Treatment of acute bacterial infection esylate glucose injection: 48 cases report
【Abstract】 AIM: To observe the curative effect and safety of gatifloxacin mesylate glucose injection for acute bacterial infection. METHODS: FortyEight cases of acute bacteria respiratory or urinary tract infection ly. The experimental subjects of the tesylate glucose or hydrochloric acid levofloxacin 200 mg (bid) for 7 to 14 days respectively. The curative effect and the adverse reaction ental group, the rate of clinical curative effect, the bacterial clearance rate, the bacterial sensitivity rate and the incidence of adverse reaction esylate glucose injection is clinically effective and safe for mon sensitive bacterial infection.
【Keyesylate (GTFX・MSL); levofloxacin; respiratory tract infections; urinary tract infections
【摘要】目的: 观察甲磺酸加替沙星葡萄糖注射液治疗急性细菌性感染的有效性及安全性. 方法: 呼吸道或泌尿道急性细菌性感染的门诊或住院患者48例,采用随机盲法对照试验,接受试验药甲磺酸加替沙星葡萄糖注射液或对照药盐酸左氧氟沙星注射液200 mg, bid,静脉滴注,疗程7~14 d,评价其疗效和不良反应. 结果: 甲磺酸加替沙星葡萄糖注射液的临床有效率、细菌清除率、%, %, %, %;%, %, %, %. 两组有效性和安全性结果经统计学分析均无显著性差异(P>). 结论: 甲磺酸加替沙星葡萄糖注射液对一般敏感菌所致的感染具有较好的临床疗效和安全性.
【关键词】甲磺酸加替沙星;氧氟沙星;呼吸道感染;泌尿道感染
0引言
甲磺酸加替沙星葡萄糖注射液是一种新的第4代氟喹诺酮类抗菌药, 目前在国内正处于临床研究阶段,我们为评价甲磺酸加替沙星葡萄糖注射液的有效性及安全性,促进临床合理用药[1-3],对48例呼吸道或泌尿道急性细菌性感染的患者给予甲磺酸加替沙星葡萄