昆明医科大学学报 2021,42 (11) :45~50 DOI: .2095- Journal of Kunmingthe diameter,circumference and area of fetal thyroid at 20-38 weeks were obtained. We found the 5th,50th and 95th percentiles increased with the gestational age,and showed a high correlation with gestational age ( r = , and , respectively) , which was statistically significant (P < );And also increased with biparietal diameter,highly correlated with the biparietal diameter (r = , and ,respectively),which was statistically significant (P < ). Conclusion In this study,we established the reference range of fetal thyroid according to different gestational ages and biparietal diameter,which is not only helpful to monitor the size of fetal thyroid at high risk for early detection of fetal goiter dysfunction,but also can assess the effect of intrauterine therapy on goiter fetuses by monitoring fetal thyroid size. [Key words] Fetus thyroid;Goiter;2-dimensional sonography;Prenatal diagnosis