带腱鞘异体肌腱移植的实验研究.pdf

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· 29· Chinese J Reparative and Reconstructive Surgery ,2001, Vol 15 (2)
带腱鞘异体肌腱移植的实验研究
张友乐王澍寰高新生尹大庆朱伟胡琪
张云涛韦加宁杨克非王红霞袁润英
【摘要】目的探讨深低温冷冻带腱鞘异体肌腱移植的可行性, 为屈指肌腱区腱鞘和肌腱缺损重建提
供新的修复材料。方法将 60 只北京双A 鸡随机分为两组, A 组为异体移植, B 组为自体移植。每组再分两个亚
组,A 1 全鞘异体肌腱移植; A 2 部分鞘(滑车A 2~A 4) 异体肌腱移植; B 1 全鞘自体肌腱移植; B2 部分鞘(滑车A 2~
A 4) 自体肌腱移植。异体材料采用深低温处理, 移植术后进行组织形态学、移植免疫学及肌腱滑动功能检测。结果
A 1 组与B 1 组移植术后局部组织反应重, 腱鞘形成生物屏障, 影响肌腱的营养致使肌腱变性, 纤维化, 部分坏死。A 2
组与B 2 组肌腱愈合良好, 组织修复能力强, 腱鞘与肌腱间可分离。带部分腱鞘异体肌腱经深低温处理后, 其组织抗
原性明显降低, 组织修复能力同自体移植, 愈合后腱鞘与肌腱间隙存在, 移植鞘与正常肌腱组织结构相同。结论
带部分腱鞘异体肌腱经深低温处理后可以作为修复腱鞘和肌腱缺损的材料。
【关键词】屈肌腱鞘异体移植低温处理
EXPERIMENTAL STUDYOF ALLOGENIC TENDONWITH SHEATH GRAFTING IN CHICKEN ZHANG You
le, WANG Shu huan , GAO Xin sheng et al. Department of Hand Surgery , Beijing Ji Shui Tan Hospital .
Beijing , P. R. China 100035
【Abstract 】 Objective To investigate availability of deep freeze stored allogenic tendon with sheath
grafting in repairing the tendon and sheath defect in the area of flexor digitorum tendon. Methods Sixty
chickens with tendon and sheath defect were divided into 2 groups randomly , group A was treated with allogenic
grafting and group B was treated with autogenic grafting , these two groups were divided into two subgroups
respectively , they were , group A 1 allogenic tendon with whole sheath grafting , group A 2 allogenic tendon with
partial