小剂量左旋甲状腺素治疗新生儿期暂时性甲状腺功能减退症的临床疗效.doc

小剂量左旋甲状腺素治疗新生儿期暂时性甲状腺功能减退症的临床疗效.doc小剂量左旋甲状腺素治疗新生儿期暂时性甲状腺功能减退
症的临床疗效
张环马晓花赵淑艳李世芳陈彤(通讯作者)
(山东省立医院<集团>东营医院257000)
【摘要】A的探讨小剂量左旋甲状腺素治疗新生儿期暂时性甲状腺功能减退症的临床疗效。方法选择我科2008年6月-2012年6月经新生儿筛查确诊为新生儿期暂时性甲状腺功能减退症42例作为实验组,对照组为甲状腺功能发育正常的新生儿42例,实验组采用小剂量左旋甲状腺素(每口 8〜9ug/kg)治疗, 对照组未给予任何治疗。结果实验组2〜3岁后停药1个月,B超、ECT示甲状腺发育正常,骨龄正常,发育商(DQ)&plUsmn;,与对照组比较差异无统计学意义(P>)o停药后1年随访,血T3、T4、TSH正常。结论小剂量左旋甲状腺素治疗新生儿期暂时性甲状腺功能减退症的临床疗效疗效显著,值得临床推广。
【关键词】小剂量左旋甲状腺素新生儿期暂时性甲状腺功能减退症临床疗效
【中图分类号】 【文献标识码】A
【文章编号】2095-1752 (2013) 30-0116-02
Clinical efficacy of small doses of levothyroxine in treatment of neonatal transient
hypothyroidism
the unit of the author: Dong Ying Hospital of SanDong
Brief introduction of the author:ZHANG Huan,female,born in 1974,Bachelor degree.
Corresponding Author:CHEN Tong E-mail: zhanghuandoctor@ 【Abstract】 Objective: To investigate the clinical efficacy of small doses of levothyroxine in treatment of neonatal transient hypothyroidism, method: Select 42
cases neonatal transient hypothyroidism diagnosed with newborn screening in our department from June 2008 to june 2012 as the experimental group and 42 cases of normal thyroid functionneonatal as the Control group. Experimental group was
accpected a small dose of levothyroxine (daily 8〜9ug/kg). The control group received no treatment Result: Experimental group withdrawal a month after 2 to 3 years, Ultrasound, ECT showing normal development of the