Nutrient mixture improves memory in patients
with early Alzheimer ’s
In clinical trial, mixture developed at MIT appears to help e
loss of connections between brain cells.
Anne Trafton, MIT News Office
ment treat
A clinical trial of an Alzheimer ’ s diseasedeveloped at MIT has found that the nutrient
cocktail can improve memory in patients with early Alzheimer ’ s. The results confirm and expand
the findings of an earlier trial of the nutritional supplement, which is designed to promote new
connections between brain cells.
Alzheimer ’ s patients gradually lose those connections, known as synapses, leading to memory loss
and other cognitive impairments. The supplement mixture, known as Souvenaid, appears to
stimulate growth of new synapses, says Richard Wurtman, the Cecil H. Green Distinguished
Professor Emeritus at MIT, who invented the nutrient mixture.
“You want to improve the numbers of synapses, not by slowing their degradation — though of
course you ’ dlove to do that too — but rather by increasing the formation of the synapses, ”
Wurtman says.
To do that, Wurtman came up with a mixture of three naturally occurring pounds:
choline, uridine and the omega-3 fatty acid DHA. Choline can be found in meats, nuts and eggs,
and omega-3 fatty acids are found in a variety of sources, including fish, eggs, flaxseed and meat
from grass-fed animals. Uridine is produ
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