Unit1ProductionofDrugsDependingontheirproductionororiginpharmaceuticalagentscanbesplitintothreegroups:(synthetics),Ⅱ.Naturalproducts,andⅢ.Productsfrompartialsyntheses(semi-syntheticproducts).资料个人收集整理,poundsofgroupsIandⅢ,however,,,,勿做商业用途Table1PossibilitiesforthepreparationofdrugsMethods -over75%ofallpharmaceuticalagents(synthetics)资料个人收集整理,(naturalproducts):资料个人收集整理,-alkaloids;enzymes;heartglycosides;harides;tocopherol;资料个人收集整理,勿做商业用途steroidprecursors(diosgenin,sitosterin);citral(intermediateproductfor资料个人收集整理,勿做商业用途vitaminsA,E,andK);peptidehormones;cholicacidfromgall;insulin)fromthe资料个人收集整理,勿做商业用途pancreas;;L-aminoacidsfromkeratinandgelatine资料个人收集整理,;L-aminoacids;dextran;targetedmodificationsonsteroids,资料个人收集整理,-hydroxylation;alsoinsulin,interferon,antibodies,peptide资料个人收集整理,勿做商业用途hormones,enzymes,(semisyntheticagents):资料个人收集整理,pounds;semisynthetic/3-lactamantibiotics;steroids;humaninsulin资料个人收集整理,勿做商业用途Severaltherapeuticallysignificantnaturalproductswhichwereoriginallyobtainedfromnaturalsourcesaretodaymoreeffectively--prepared..-aminoacids,Chloramphenicol,Caffeine,Dopamine,Epinephrine,Levodopa,peptidehormones,Prostaglandins,D-Penicillamine,Vincamine,,勿做商业用途Overthelastfewyearsfermentation-,(yeastsandmoulds)andProkaryonts(singleba
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