223例多发性硬化患者中医辨证分型研究.doc

223例多发性硬化患者中医辨证分型研究
【摘要】目的探讨多发性硬化(MS)中医基本证候的分布情况,为其辨证分型标准的最终确立做有益的尝试。方法回顾性分析223例MS患者一般资料及中医四诊信息,病例分析结合现代数理统计方法,确立所收集病例的证型。结果体倦乏力、神疲懒言、肢体无力、眩晕、肢麻沉重等出现频率在60%以上,积分排序位于前5位,体现了MS的主要证候特征。5个基本证候为:瘀阻经络证(%),舌紫黯为本型最重要的影响因素;湿热阻络证(%),苔黄腻为本型最重要的影响因素;阴虚络阻证(%),脉细数为本型最重要的影响因素;肝风内动、风痰阻络证(%),肢体抽搐为本型最重要的影响因素;气血两虚、经气不利证(%),脉虚为本型最重要的影响因素。结论本病病位在经络,病性为瘀血、湿热、阴虚、风痰、气血两虚,体倦乏力、神疲懒言、肢体无力、眩晕、肢麻沉重等为MS的主要证候特征。
【关键词】多发性硬化;中医四诊;辨证分型;聚类分析;Logistic回归分析
Abstract:Objective To investigate the distribution regularity of TCM science basic syndrome for multilple sclerosis (MS). Methods Through retrospective analysis for general data of case 223 patients and the information of TCM diagnosis with the method of case analysis and modern mathematical statistic, the syndrome types of the case collected were established. Results General fatigue, weariness and no desire to speak, quadriplegia, megrim, acroanesthesia and so on, which reflect the main symptoms of MS, with occurrence frequency of above 60 percent. F
ive basic symptoms:Syndrome of haemostasis blocking collaterals (%), dark purple tongue is the most important factor;Syndrome of dampness-heat blocking collaterals (%), yellow greasy furred tongue is the important factor;Syndrome of yin-asthenia and obstruction of collateral (%), rapid and thining pulse is the important factor;Syndrome of endogenous wind of liver and obstructio