人体胆结石高能震波碎石的动物实验.doc

人体胆结石高能震波碎石的动物实验
作者:屈学民王青庭王斯刚马庆久张建保文峻杨继庆
【关键词】高能震波
键词: 高能震波;胆结石;碎石术;犬
摘要:目的研究人体3种胆结石在一定能量下,冲击次数和能量的关系,确定不损伤胆囊和小肠内膜的能量安全阈值. 方法犬胆囊和小肠内放入固醇石、混合石和色素石,在不同的输出电压下,放电碎石. 结果固醇石、混合石和色素石破碎所需的能量不同,在同样电压下,固醇石所需的次数最少,混合石次之,色素石最多;病理检查表明,在电压<15kV时,胆囊和小肠粘膜处,细胞膜轻度充血,>15kV后,粘膜有脱落,膜下组织水肿. 结论电压具有依赖性;该仪器临床应用的冲击电压应小于15kV.

Keywords:high energy shock wave;cholelithiasis;lithotri-ty;dogs

Abstract:AIM To study the effect of shock wave on sterol bination calculus and pigment stone and determine the threshold which can make them fragmentation without tissue The stones were put in the small intestine and gallbladder of canine and different volt-ages were used to shock them by
There were different effects of shock wave on the three kinds of the same voltage in order to crush the stone the least times is needed for sterol stone,and bination calculus,the times needed for pigment stone was the study showed that15kV voltage could be the threshold value which might damage the small intestine and There is dependence of energy on voltage used in clinic should be less than15kV.

0 引言

胆系统结石的发病率较高,严重影响了人体的健康,可以引起疼痛、影响消化系统,还可以阻塞胆囊颈及胆总管而引起绞痛、发热、黄疸,%~8%.原发性肝内外胆管结石患者发病率占胆结石患者的50%,其死亡率较高,,胆道术后残石率仍高达30%~96%.