不同剂量头孢呋辛辅助治疗aecopd的临床效果观察.doc

不同剂量头孢呋辛辅助治疗AECOPD的临床效果观察[摘要]目的探讨不同剂量头孢呋辛辅助治疗慢性阻塞性肺疾病急性加重期(AECOPD)的临床效果。方法将80例AECOPD患者根据入院顺序分为治疗组与对照组,每组各40例,两组均给予序贯机械通气治疗,对照组辅助大剂量头孢呋辛治疗,治疗组辅助小剂量头孢呋辛治疗。%%,两组差异无统计学意义(P>)。治疗组的FEV1、FEV1/FVC与PEF值与对照组比较差异无统计学意义(P>)。治疗组口干、尿潴留等不良反应发生率明显低于对照组,差异有统计学意义(P<)。结论小剂量头孢呋辛辅助治疗AECOPD,能在保持良好疗效的基础上降低不良反应发生率,值得推广应用。[关键词]慢性阻塞性肺疾病;头孢呋辛;剂量[中图分类号]R563[文献标识码]A[文章编号]1674-4721(2014)05(a)-0064-03TheclinicaleffectobservationofdifferentdosesofcefuroximeadjuvanttreatmentAECOPDWANGFeiIntensiveMedicineDepartment,People′sHospitalofYanlingCountyinHenanProvince,Yanling461200,China[Abstract]ObjectiveToinvestigatetheclinicaleffectsofdifferentdosesofcefuroximeadjuvanttreatmentwithchronicobstructivepulmonarydiseasewithacuteexacerbation(AECOPD).Methods80casesofchronicobstructivepulmonarydiseasewithacuteexacerbationwereequallydividedintotreatmentgroupandcontrolgroupunderhospitalorder,allcasesweregivensequentialmechanicalventilationtherapy,thecontrolgroupweregivenhigh-dosecefuroximeadjuvanttreatment,andthetreatmentgroupweregivenlow-,%%respectively,thedifferencesbetweenthetwogroupshadnostatisticalsignificance(P>).TheFEV1,FEV1/pared(P>).Theincidenceofadversereactionsofdrymouth,urinaryretentionofthetreatmentgroupweresignificantlylessthanthe