,15(1):】22MLouStiles,]enJT,etatS*,abi]ityofondam~tronhy—drceh!ofideinportabLeinfusionpmnpreservoirsAmJHaspphann,(7):14713MotatserratM,Vi~,etStabi~tyofifosfin~idein09%sodiumchloridesolutionorwste~forinjectioninBportableivpumpca?,1992,49(5):1137(1998年7月20日收籍)丹一340高效液相色谱法测定盐酸苯乙双胍片的含量邢玉仁马洁(山东省医药工业研究所济南250100),?..._.,7./YR',摘要目的::采用反相C色谱柱,m甲醇一醋酸盐缓冲液(pH42)(55:45)为流动相,,:盐酸苯乙双胍在8,56?rrd的浓度范围内呈良好线性(r=09994),%,RSD为084%:结论:本法可用于谈片荆的刹定,,茎墼茎刍墨鉴t笠立LDeterminationofphenforminhydrochlorideintabletsby卸PLC?ngYuren,MaJie(ShangdongIrLstituteofPham~)ABSI~(脚?rlTvE:HPLCmethodwaseStableddetermintationofDherdotmtnhydroeh!ofidetablesME?onditionsc】Beoltavm,mobilephaseofmethanol-acetatebuffer()(55:45)and234l?fordetectionintermalstandardwasdiprophyllineR1?I胚:There??agoodlinearrelationshipwiththeconcentrationrangeof8—56'mlphen—forminhydmchloride(r=),theaveragerecoverywas999%.therelativestandarddeviation雌084%.CONCLUSIONS:ThemethodjSselective,s~~,,中国药典采用半微量定氮法,操作繁琐,专属性差,,由于我们的处方中所使用的辅料有干扰,,建立了HPLC法,可用于该片剂的含量测定,操作简便,,510型泵,486型紫外检测器;沃特斯一大
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