熊去氧胆酸治疗非酒精性脂肪肝30例临床观察.doc

熊去氧胆酸治疗非酒精性脂肪肝30例临床观察[摘耍]冃的观察熊去氧胆酸治疗非酒精性脂肪肝的疗效。方法非酒精性脂肪肝患者分为治疗组30例,应用熊去氧胆酸钠胶囊(优思弗胶囊)250mg,每日3次,口服,疗程为6个月。对照组30例,应用多烯磷脂胆碱胶囊(易善复胶囊)456mg,每冃3次,口服,疗程为6个月。观察治疗前后肝脏B超、生化指标、肝脏大小和症状变化。结果治疗后肝脏B超、牛•化学指标、症状明显改善,与易善复比较无统计学意义,无明显不良反应。结论熊去氧胆酸治疗非酒精性脂肪肝安全有效,值得临床推广使用。[关键词]熊去氧胆酸;非酒精性脂肪肝[[文献标识码]B[文章编号]1673-9701(2011)24-85-02TheTherapeuticEffectofUrsodeoxycholicAcidinTreatmentofNonalcoholicFattyLiver:AClinicalObservationof30CasesYANGYideHOUWeiTaizhouMunicipalHospitalinZhejiangProvince,Taizhou318000,China[Abstract]-alcoholicfattyliverweredividedintotwogroupswith30casesineach,thetreatmentgroupof30caseswhichreceivedursodeoxycholicacidcapsulesof250mg, 3timesaday,oralingestion,treatmentfor6months,andcontrolgroupof30caseswhichreceivedpolyenephosphorylcholinecapsule(Essentialecapsules)of456mg, 3timesadayoralingestion,-scanliver,biochemicalparameters,,liverultrasonography,biochemicalindicators,,-alcoholicfattyliverisverysafeandeffective,worthyinclinicalwidely.[