进展性脑梗死患者血清IL1β、IL6水平研究.pdf

成都医学院学报 013年第8卷第4期 JournalofChengdu medicalCollege 013 '475'
网络出版地址:http: s detail . 013080 .
doi: .- 57.
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进展性脑梗死患者血清IL-l!~IL-6水平研究
余晓峰陈祥华林亚琴
(江苏省东台市人民医院神经内科东台 4 00)
摘要目的分析进展性脑梗死(PCI)患者血清白细胞介素-1p(IL-1p)~白细胞介素-6(IL-6)水平探讨其可
能的发病机制0方法 66例脑梗死患者根据入院后病情进展情况分为进展组和非进展组各33例;根据梗死体积
分为小梗死组~中梗死组~大梗死组各例0另选取健康体检人员40例为对照组0清晨空腹时取静脉血5mL
取血清 ELISA 法检测IL-1p~IL-6水平0结果非进展组和进展组患者血清IL-1p~IL-6水平均明显高于对照组;
进展组血清IL-1p~IL-6水平明显高于非进展组0中~大梗死组患者血清IL-1p~IL-6水平明显高于小梗死组大梗
死组患者血清IL-1p~IL-6水平明显高于中梗死组0大梗死组 PCI发生率明显高于小梗死组0结论脑梗死患者
血清IL-1p~IL-6水平与梗死体积有关且对 PCI发生具有早期预警意义0
关键词脑梗死;白细胞介素-1p;白细胞介素-6
中图分类号 文献标志码 B
StndyontheLevelsofSernmInterlenkin-l!andInterlenkin-6inpatientswithprogressivecerebralInfarction YU
Xiao-feng CHEN Xiang-hua LINYa-9in (DePartmentof Neurology DongtaipeoPle'SHoSPital Dongtai
4 00 China)
Abstract Objective toanalyzethelevelsofseruminterleukin-1p (IL-1p)andinterleukin-6 (IL-6)in
Sixty-sixpatientsWith
cerebralinfarction Were divided into progressive group and non-progressive group according to pathological
progressionafteradmissionintohospital middleandlarge
infarctiongroups mLof
venou