sh3007-2007 石油化工储运系统罐区设计规范.pdf

国内图书分类号:TH89 学校代码:10213 国际图书分类号:621 密级:公开工程硕士学位论文无创血糖检测与胰岛素剂量控制设计与实现研究硕士研究生:朱磊导师:孙兵申请学位:工程硕士学科:仪器仪表工程所在单位:电气工程及自动化学院答辩日期:2014年7月授予学位单位:哈尔滨工业大学万方数据 Classified Index: TH89 : 621 Dissertation for the Master Degree in Engineering DESIGN AND REALIZATION OF NON-INVASIVE BLOOD GLUCOSE MONITORING AND INSULIN DOSE CONTROL Candidate: Zhu Lei Supervisor: Sun Bing Academic Degree Applied for: Master of Engineering Speciality: Instrumentation Engineering Affiliation: School of Electrical Engineering and Automation Date of Defence: July, 2014 Degree-Conferring-Institution: Harbin Institute of Technology 万方数据哈尔滨工业大学工程硕士学位论文 I-I- 摘要在日常生活中,糖尿病已经对人们的健康与生命安全带来了全球性的重大威胁。进行糖尿病的治疗时,为了对临床用药进行合理指导,降低并发症发病率, 往往需要实施连续的血糖检测工作。本研究的主要理论基础是红外漫反射检测原理,将无创血糖检测和胰岛素剂量控制结合在一起。 2530单片机的胰岛素泵设计方案,2530单片机作为控制核心,通过驱动步进电机推进专用注射器活塞,为患者注射胰岛素。系统的硬件部分主要有:血糖检测模块、显示模块、ZigBee无线通讯模块、步进电机及其驱动模块、传感器模块、时钟模块和中央处理模块。首先在进行血糖检测时,应该将有创检测得到的血糖浓度值与近红外漫反射光谱所检测出来的数据结合在一起建立数据模型;检测过程中,依靠创建好的模型和检测获得的光谱数据,对糖尿病患者的血糖浓度值进行适当估计。系统整体选用了光纤结构,有效简化了光路系统,优化光纤测头,使其与受测量部位更加贴合,操作难度低,方便上手。并且实现了步进电机的驱动和ZigBee 无线传输技术,通过LCD可以显示血糖浓度的大小和电机注射的胰岛素含量。关键词:无创血糖检测;单片机;步进电机;胰岛素泵,ZigBee 万方数据哈尔滨工业大学工程硕士学位论文-II- Abstract Diabetes and plications have e a serious threat to human health and safety worldwide disease. In the course of the treatment of diabetes, continuous glucose monitoring to guide rational clinical use of drugs, reduce the risk plications has an important role. In this paper, the near-infrared diffuse reflectance detection principle, the blood glucose monitoring systems and insulin bine to form a closed loop system. Based on microcontroller, this paper gives a design scheme of open-loop portable insulin pump, using three batteries as a power supply, CC2530 MCU as the control core, propelling special syringe plunger and injecting insulin into a patient’s body by driving the stepper motor. System hardware consists of six functional modules: the centra