贫血及贫血性心脏病夜.pptx

Anemia AND Anemia Heart Disease
2
Definition
Anemia is defined as a decrease in the circulating RBC, hemoglobin or the hematocrit ,and a corresponding decrease in the oxygen-carrying capacity of the blood.
Normal values of the hemogram (In sea level):
TEST WOMEN MEN
HCT (%) 37-48 40-50
Hb (g/L) 110-150 120-160
RBC Count(1012/L) - -
PS: The HB of Newborn is170-200g/L.
3
Diagnosis
WOMEN MEN PREGNANT
Hb (g/L) ＜ 110 ＜ 120 ＜ 100
WOMEN
■ Anemia isn’t a diagnosis,
it is a sign of the presence of disease.
■ Correct diagnosis: include underlying cause of the anemia
■ They can be altered by the plasmatic volumes .
■ The mean normal value depends on :altitude of residence,
age and gender.
■ Difference between women and men values
are due to androgen hormones.
4
Diagnosis
First step :
detection of the presence of anemia,and the severity.
Second step:
laboratory investigation of the morphological classification.
Third step:
investigation of the pathogenesis of anemia.
5
Diagnosis
Mild
120/110
Moderate
90
Severe
60
Very Severe
30
Classification according to severity
First step:
6
Diagnosis
cell morphological type MCV（fl） MCH(pg) MCHC (%)
Macrocytic anemia >100 >34 32～36
Normocytic anemia 80～100 27 ～34 32～36
Microcytic hypochromic
anemia
Simple microcytic
anemia
(80-100)
(32-36)
(27-34)
<80 <27 <32
<80 <27 32～36
Second step:
cell morphological classification
PS: According to Bone marrow proliferative degree and
peripheral RBC morphology .
7
Diagnosis
Third step: according to etiology/pathogenesis