肝癌肝移植的米兰外标准.ppt

This presentation is reproduced on this site with the permission of the author (s). All opinions , research citations and analyses are those of the author (s) and may not reflect those of OPTN/UNOS committees or the OPTN/UNOS Board of Directors . Liver Transplantation for HCC Beyond the Milan Criteria Charles M. Miller, MD The Recanati -Miller Transplantation Institute Mount Sinai Medical Center New York, NY This presentation is reproduced on this site with the permission of the author (s). All opinions , research citations and analyses are those of the author (s) and may not reflect those of OPTN/UNOS committees or the OPTN/UNOS Board of Directors . LONG TERM RESULTS OF LIVER TRANSPLANTATION AND MULTIMODAL ADJUVANT THERAPY FOR THE TREATMENT OF HEPATOCELLULAR CARCINOMA LARGER THAN 5CM Sasan Roayaie, Sukru Emre, Thomas Fishbein, Patricia Sheiner, Charles Miller, and Myron Schwartz The Recanati-Miller Transplantation Institute Mount Sinai Medical Center New York, NY Annals of Surgery Vol. 235, No. 4 533-539 April, 2002 This presentation is reproduced on this site with the permission of the author (s). All opinions , research citations and analyses are those of the author (s) and may not reflect those of OPTN/UNOS committees or the OPTN/UNOS Board of Directors . Background: HCC ? mon an tumor worldwide ? one million deaths annually ? incidence rising in US – per 100,000 ? good survival with transplant for tumors ? 5cm – 75% at 4 years ? poor survival with transplant for tumors ? 5cm – 18-30% at 5 years This presentation is reproduced on this site with the permission of the author (s). All opinions , research citations and analyses are those of the author (s) and may not reflect those of OPTN/UNOS committees or the OPTN/UNOS Board of Directors . Previous Studies study year (n) (n) with HCC ? 5cm median f/u survival Stone et al -Baylor chemo 1993 20 17 mo 54%-3yr Carr et al -Pitts