肠道病毒感染在儿童急性呼吸道感染中的临床特征及流行病学分析 [摘要] 目的 了解?c道病毒在急性呼吸道感染中的临床及流行病学特征。 方法 选取2014年3月～2016年3月南方医科大学附属深圳妇幼保健院儿科门诊及病房急性呼吸道感染共计13 472例患儿作为研究对象，进行肠道病毒筛查。其中，肠道病毒通用核酸定量阳性病例1222份，进行肠道病毒分型鉴定，分析其临床及流行病学特征。 结果 13 472份鼻咽部拭子标本中共检出肠道病毒阳性1222例，其中，EV71阳性150例，CVA16阳性266例，CVA6阳性230例，其他hEV阳性576例；∶1；年龄最小的5 d，最大的12岁，；5岁以下是肠道病毒感染的高发年龄段，EV71、CVA16、CVA6感染高发年龄为6个月～5岁，而在其他hEV感染中2岁以下婴幼儿更容易高发。每年4～7月是肠道病毒流行感染高峰期，主要引起手足口病及疱疹性咽峡炎，症状以发热、皮疹为主，但在其他hEV感染中，以咳嗽、喘息等症状为主要表现的呼吸道感染比例升高，差异有统计学意义（P [关键词] 肠道病毒；急性呼吸道感染；感染谱 [中图分类号] [文献标识码] A [文章编号] 1673-7210（2016）12（c）-0105-04 [Abstract] Objective To explore the clinical and epidemiological characteristics of children with enterovirus （EV） infection in acute respiratory tract infection. Methods 13 472 cases who were diagnosed with acute respiratory tract infection （ARTI） in the Pediatric Outpatient and Wards of Shenzhen Maternity and Children's Hospital Affiliated to Southern Medical University from March 2014 to March 2016 were screened for EV. 1222 positive cases of EV were collected to identify the types of EV and analyze the clinical and epidemiological characteristics. Results There were 1222 EV positive cases among 13 472 nasopharyngeal swab specimens， among which， 150 patients had EV71 positive， 266 patients had CVA16 positive， 230 patients had CVA6 positive and 576 cases had other hEV positive. The sex ratio was ∶1. The y
