山西医科大学硕士学位论文 I 中低位直肠癌全系膜切除术后吻合口瘘危险因素的分析中低位直肠癌全系膜切除术后吻合口瘘危险因素的分析中低位直肠癌全系膜切除术后吻合口瘘危险因素的分析中低位直肠癌全系膜切除术后吻合口瘘危险因素的分析中文摘要中文摘要中文摘要中文摘要目的研究中低位直肠癌全系膜切除术后吻合口瘘的发生率和危险因素, 为临床减少瘘的发生率和行预防性肠造瘘提供参考依据。方法回顾性分析 2006 年 1 月至 2009 年 7 月间在南方医科大学附属南方医院实施 TME 手术患者 125 名, 将患者分为吻合口瘘及无吻合口瘘两组,采用 X 2 检验对各个影响因素进行单因素分析,及各个影响因素进行 Logistic 回归分析。结果术后吻合口瘘的发生率为 % ( 12 / 125 ) , 发生吻合口瘘的平均时间为术后 。吻合口瘘的发生与年龄、糖尿病、术前放化疗、血清白蛋白、吻合口水平和吻合技术等因素密切相关,与性别、体重指数、浸润程度、分期、高血压、红细胞、血红蛋白、血清总蛋白、手术方式和肿瘤大小等无关。多因素回归分析表明糖尿病、术前放化疗、吻合口水平和低白蛋白是决定吻合口瘘发生的独立因素( P < ) 。结论中低位直肠癌全系膜切除术后吻合口瘘的发生率 % 。糖尿病、术前放化疗、肿瘤下缘与肛门距离< 5cm 和低白蛋白为中低位直肠癌全系膜切除术后吻合口瘘的危险因素。关键词中低位直肠癌全系膜切除术吻合口瘘危险因素预防性造瘘山西医科大学硕士学位论文 II R R R R isk isk isk isk factors factors factors factors analy analy analy analy sis sis sis sis for for for for anastomotic anastomotic anastomotic anastomotic f f f f istula istula istula istula after after after after total total total total mesorectal mesorectal mesorectal mesorectal excision excision excision excision of of of of low low low low colorectal colorectal colorectal colorectal cancer cancer cancer cancer A A A A bstract bstract bstract bstract Objective Objective Objective Objective To study risk factors and hanpenning rates of anastomotic fistula after total mesorectal excision( TME TME TME TME )in low colorectal cancer patients. In order to provide the reference for preventive fistula and reduce hanppenning rates of anastomotic fistula. Methods Methods Methods Methods Clinical data were analyzed from 125 patients in southern medical university hospital who underwent total mesorectal excision ( TME TME TME TME )for low colorectal cancer between January 2006 and July 2009 . and divided 125 patients into anastomosis and no anastomosis (two groups), using x 2 inspection and Logistic regression analysis about various influence factors. Results Results Results Results A nastomotic fistula after total mesorectal excision ( TME TME TME TME )occurred in 12 cases % (12/125). The median time of anastomotic fistula after op
