童喘清颗粒治疗哮喘缓解期患儿60例临床的分析研究.pdf

中文摘要目的哮喘是JJ',JL时期常见的中医肺系疾病,是一种反复发作的痰鸣气喘疾病。目前哮喘已是一个全球关注的公共健康问题,也是儿童至成人期最常见的慢性疾病。儿童哮喘如果不及时诊治,严重者有可能因缺氧导致呼吸困难甚至窒息,后果不堪设想。因哮喘缓解期患儿无疾病相关症状或症状轻微,尽量长时间的维持在此阶段是医师和患者的共同目标,所以保持在缓解期预防发作是哮喘最关键的治疗环节。我们以益气培元,平喘止咳, 化痰下气为法,观察童喘清颗粒治疗哮喘缓解期虚哮证的疗效。方法60例哮喘缓解期患儿采用分层区组随机设计法,分为实验组与对照组,每组各30例。分两级设盲:一级设盲以A组、B组表示,二级设盲再分别指定A组、B组的实验组、对照组的归属。实验组(A组)予童喘清颗粒,规格:颗粒剂,39/袋。对照组(B组)予安慰剂,规格:颗粒剂,39/袋。外包装、颜色、气味等应尽可能与原制剂相同。试验时间为 4周±4天,患儿服药期间每周访视1次,观察患儿日间症状,夜间症状/ 憋醒,活动受限、咳嗽、自汗、面色少华、神疲懒言、舌象、脉象及肺功能等变化,并观察服药后不良反应。控制病例临床用药结束后满1 2周±6 天进行随访,再次评估哮喘控制情况。%,%;对照组临床控制率 %,%;两组差异有统计学意义(P<)。结论童喘清颗粒可以缓解患儿临床缓解期症状,改善肺通气功能,对哮喘缓解期虚哮证患儿有明显疗效,其作用机理与减轻气道阻塞,调节免疫反应及抑制气道炎症等多个环节有关。关键词童喘清颗粒;哮喘缓解期;虚哮证;儿童;临床研究。 Ch-Id out ofclear particIes treatment of asthma Remi SS on 60 cases of ch dren ofthe ca research Spec a st:Tradi tionalChinese Medicine Hu Tutor:Xi×iong X ang ABSTRACT Object ive Asthma Schildren per iod mon pulmonary di sease, Sarepeated attacks ofphlegm sound asthma asthma Salready ag obal concern of the publ chea 1thprobl em,a SO i S thechi1dren toadulthood the mon chroniC asthma if not timely diagnosi Sand treatment,because of lack of oxygen S ikely tolead torespiratory difficul ty even suffocation, consequence asthma remi SSion of children of the di sease associated symptoms or no symptoms minor,and try to maintain a long time at thi S Stage i S mon goal of doctors and pat ent S,SO remi SS on prevent on attack i S the key 1ink of asthma toschool yiqi,flat out ofcough,el iminating phlegm tothegas for the law,observe child out ofClear part icles tTeatment ofasthma remiSSion curative effect. Methods 60pat ent swith asthma remi SSionchi dren by Stratified area group then design method,the experimental group and control group Sdivided into,each group of each 30 level set blind:level 1set ingroup Ablind,said group B,level 2 set again specifled group Ablindrespectively,group Bgroup,the ownershiP of t