: . 奥扎格雷钠联合黄芪注射液治疗糖尿病 肾病的疗效观察医学论文 $ 本文由中国论文范文收集整理。 作者:孙志刚董建芳孙海鹏 【摘要】 目的:观察奥扎格雷钠与黄芪注射液联合 治疗 糖尿病肾病的疗 效。方法:将84例早期糖尿病肾病患者随机分为 3组,每组28例,在常规 治疗的基础上,A组加用黄芪注射液,B组加用奥扎格雷钠注射液,C组加用黄 芪注射液与奥扎格雷钠注射液,疗程均为 20d。观察治疗前后各组尿白蛋白排 泄率(UAER,血尿素氮(BUN,血清肌酐(SCr),糖化血红蛋白(HbAlc) 的变化。结果:糖化血红蛋白,血清肌酐,血尿素氮,尿白蛋白排泄率: 3组 治疗后均比治疗前显著下降(P<001),C组下降幅度优于A组和E组 (P<005。结论:奥扎格雷钠联合黄芪注射液治疗糖尿病肾病能降低糖化血红 蛋白,显著降低尿白蛋白排泄率,同时改善肾功能。 【关键词】 黄芪注射液;奥扎格雷钠;糖尿病肾病 【ABSTRACT Objective: To i nvestigate the therapeutic effect of mickvetch injection(Ml) combined with Aozhagelei injection on earlydiabetic n ephropathy(EDN). Methods: 84 patie nts with EDN were ran domly divided in to three groups, with 28 in each conven ti onal hypoglycemic therapy for the patie nts in all groups, patie nts in group A were treated with MI, for group B with Aozhagelei injectio n and group C with Aozhagelei plus MI respectively. The therapeutic course for all patie nts was 3 related in dices of EDN before and after treatme nt were determ ined and compared,i nclud ing blood urea n itroge n(BUN), Serum creat inine (SCr ),uri nary albumin excreti on rates(UAER)a nd,HbAlc. Results: the levels of BUN, SCr, HbAlc, and UAER were significantly decreased in all 3groups(P<001).a nd the decreaseme nt in Group C was more sig nifica nt tha n that of the other two groups (P<005).